Dr. Lim’s research focuses on translational neuroscience, investigating state-of-the-art neuromodulation and pharmacological treatments for neuropsychiatric disorders. More specifically, he aims to elucidate the neural underpinnings of mood and anxiety disorders, along with neurodegenerative diseases, notably Alzheimer’s and Parkinson’s disease, and other age-related cognitive disorders. His work draws on interconnected methodologies spanning cellular and molecular techniques, electrophysiology, and behavioral and neurochemical assays. Collectively, these tools enable a multidisciplinary framework for examining how neurostimulation interacts with brain networks by modulating neuronal activity and the brain’s microcellular environment.
Research Interests: Preclinical and translational research of neurological and psychiatric disorders.
Neuromodulation: DBS (electrical/nanoparticle-mediated/optogenetic), VNS, TMS, & tDCS.
Neuropsychopharmacology: Lac-Phe, medicinal mushrooms, Ganoderma lucidum, & melatonin.
Disease models: Depression, Alzheimer’s disease, Parkinson’s disease, Aging, & Hepatocellular Carcinoma models.

